ENIGMA-MDD is a working group of the ENIGMA consortium aimed at imaging markers discriminating MDD patients from healthy controls using an individual participant, data based meta-analysis.
The ENIGMA MDD working group is an international collaboration currently including 35 research samples from 14 different countries worldwide, including brain scans from around >5,000 MDD patients and >9,000 controls. The NESDA imaging study is part of this consortium.
The primary aim of our ENIGMA-MDD Working Group is to identify imaging markers that robustly discriminate MDD patients from healthy controls across many different samples using carefully a priori planned, standardized image processing and statistical analysis protocols. The ENIGMA MDD working group is led by Lianne Schmaal (chair) and prof. Dick Veltman (co-chair).