REST study

Research project

With the REST study (REgistering Sleep during Trauma treatment) Hein van Marle aims to translate basic findings on the role of sleep in emotional memory to the patient-level in PTSD.

A growing literature highlights the role of sleep in emotional regulation and memory. These findings suggest that sleep is essential in the treatment of post-traumatic stress disorder (PTSD). In this Amsterdam Neuroscience Alliance project, Hein van Marle is out to identify the role of sleep in ongoing PTSD treatment by assessing the day-to-day interrelatedness between different sleep parameters (like duration of slow wave sleep, sleep spindle count and REM-fragmentation) and treatment outcome during an existing 5-day PTSD treatment program. Sleep will be registered every night using a single-lead ambulatory EEG-device.

Findings from the project may guide the development of new, sleep-related interventions in PTSD, like EEG-guided sleep deepening and pharmacological strategies to consolidate REM-sleep.

Contact information

Researchers involved

Go to Top