In an effort to understand how the regional involvement of dopamine signaling promotes healthy and pathological behavioral functions, Lizz employs behavioral paradigms that disentangle two of dopamine’s main functions: reward prediction and movement. Lizz applies fiber photometry and optogenetics in freely behaving animals to measure and manipulate pre- and postsynaptic dopamine signaling in several striatal regions and/or related to a specific basal ganglia output pathway (“D1” or “D2”)

More information