Contactperson

Nienke Vulink, n.c.vulink@amsterdamumc.nl

Research themes

Misophonia is a recently identified disorder of decreased sound tolerance, typically developing during childhood or early adolescence. Misophonia can have a serious impact on the lives of children and families. Thus far, no validated Dutch questionnaires to assess misophonia in youth, and no evidence-based treatment for misophonia specifically in children and adolescents existed.

This study aims to

  1. Develop and validate two innovative questionnaires for screening and severity assessment of misophonia in youth, and
  2. Investigate the efficacy of combined CBT+PMT group treatment for misophonia in youth.

For the first aim, we developed the (child- and parent-reported) Misophonia Screening List – Child and Youth and the AMISOS-Y. And (after instrument refinement) an extensive iterative validation process is performed consisting of ROC curve, reliability, and principal component analyses, and assessment of concurrent, convergent and divergent validity, on a combined sample. Clinical sample: 95 children/adolescents with misophonia and their parents. Control group 197 children/adolescents from the general population and their parents.

For the second aim, a RCT is conducted. In this RCT a clinical sample of 95 children/ adolescents with misophonia is randomly assigned to either a direct CBT+PMT treatment condition or a waiting list control group. At three time points (baseline, 3 months, 6 months) we assess severity of misophonia, misophonia screening scores, emotional/behavioral problems, attention problems, sensory processing and quality of life. We also assess clinical change and social validity of the treatment, and explore predictors of treatment outcome.

This project is a collaboration between the department of Psychiatry Amsterdam UMC and Levvel. And is funded by Fonds SGS, een innovatiefonds van Zilveren Kruis.